ABSTRACT
AbstractSevere cutaneous drug reactions include a wide spectrum of clinical manifestations ranging from mild morbilliform cutaneous rash, to severe forms of hypersensitivity. Special attention is given in this report to the acute generalized exanthematous pustulosis (AGEP), induced in 90% of cases by the use of systemic drugs, especially aminopenicillins and macrolides. The incidence of the disease is low, 1-5 cases per million patients / year. The main differential diagnosis is Von Zumbusch's Pustular Psoriasis. The prognosis is generally good and the disease self limited, after withdrawal of the triggering drug. In this report the authors describe a case of AGEP, triggered by ceftriaxone in a patient with psoriasis vulgaris.
Subject(s)
Aged , Humans , Male , Acute Generalized Exanthematous Pustulosis/etiology , Acute Generalized Exanthematous Pustulosis/pathology , Anti-Bacterial Agents/adverse effects , Ceftriaxone/adverse effects , Psoriasis/pathology , Biopsy , Diagnosis, Differential , Psoriasis/chemically inducedABSTRACT
A autora relaciona as diversas manifestações clínicas da infecção pelo papilomavírus humano em Pediatria com ilustrações, menciona seu diagnóstico clínico e histopatológico e apresenta os vários tipos de tratamento, indicados ou não, nas múltiplas formas da moléstia, bem como sua prevenção.